Jasper Newton “Jack” Daniel came into work early one morning before anyone else had arrived at the distillery. He wanted to complete some paperwork and needed to open the safe. He had trouble remembering the combination and grew so frustrated that he kicked the safe with his left foot. Instead, the blow to his big toe gave him a nasty infection and his foot had to be amputated.The gangrene continued to spread throughout his system and he eventually lost his left leg due to poor blood circulation. He died due to complications from the gangrene infection on Oct. 9, 1911 at the age of 61.